For each composite component, the user is prompted for the anticipation of: the probability of having the event (or an interval in which this probability takes values); the effect relevant to detect (measured either by the odds ratio, risk ratio or risk difference). The correlation between the components is also required.
- P1, the probability of successes for the Endpoint1 in Control Group
- P2, the probability of successes for the Endpoint2 in Control Group
- D1, the effect on the Endpoint1
- D2, the effect on the Endpoint2
- Lower and upper bounds for the correlation when the correlation is assumed equal in the two groups
- Lower and upper bounds for the correlation when the correlation for each group
- Probability of the composite endpoint
- Probability of the overlap: probability of the intersection of both outcomes.
- Relative overlap: the ratio between the probability of the intersection and the probability of the composite endpoint.