CompARE

Welcome to CompARE

Designing feasible clinical trials

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What is CompARE?



CompARE is a web-platform inspired to provide help on issues relating to trials with composite endpoints. CompARE may be used as a tool for calculating the elements needed in the planning phase of clinical trials involving composite endpoints. With its user-friendly interface, CompARE allows to input the main parameters included in the trial -such as the treatment effect on the components of the composite endpoint, and its frequencies of occurrence- and helps provide power and sample size calculations among others.

Apps



CompARE is split into two apps for time-to-event and binary endpoints, respectively. They are implemented with the Shiny R package

Features



Effect Size

Studying the treatment effect for the composite endpoint

Time to event       Binary

Sample Size

Computing the number of patients under different scenarios

Time to event       Binary

Endpoint Selection

Identifying the best endpoint combination for the design

Time to event       Binary

Association

Assessing the degree of association between components

Binary

About us


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Lupe Gómez Melis

Personal Web-page
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Marta Bofill Roig

Personal Web-page
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Jordi Cortés-Martínez

Personal Web-page

Our Expertise


Talks


  1. G. Gómez, J. Cortés and M. Bofill (2019-07-15). CompARE: a web app to study Composite Endpoints. 40th Annual Conference of the International Society of Clinical Biostatistics (ISCB 2019, Leuven)
  2. J. Cortés and G. Gómez (2018-07-09). CompARE: Sample Size Calculation for Time-To-Event Composite Endpoints. XXIXth International Biometric Conference (IBC 2018)
  3. M. Bofill and G. Gómez (2018-07-09). Sample Size Derivation for Composite Binary Endpoints Accounting for Departures of the Anticipated Values. XXIXth International Biometric Conference (IBC 2018)
  4. M. Bofill and J.L. Jiménez (2018-01-19). Facing the challenges in clinical trials. III Jornadas Científicas de Estudiantes de la Sociedad Española de Biometría.
  5. J. Cortés, M. Bofill and G. Gómez (2018-01-19). Sample size calculation using CompARE. III Jornadas Científicas de Estudiantes de la Sociedad Española de Biometría.
  6. M. Bofill and G. Gómez (2017-09-07). Clinical trial designs with multiple binary endpoints. Congreso de Jóvenes Investigadores Real Sociedad Matemática Española.
  7. G. Gómez (2017-09-07). Non-proportional hazards: consequences on sample size. Conferencia Española de Biometría.
  8. M. Bofill and G. Gómez (2017-09). Clinical trial designs with multiple binary endpoints. Conferencia Española de Biometría.
  9. M. Bofill and G. Gómez (2017-07-10). Sample size derivation for binary composite endpoints. Annual Conference of the International Society of Clinical Biostatistics.
  10. G. Gómez (2017-05-26). Sample size considerations for composite endpoints. Conference on Lifetime Data Science.
  11. M. Bofill and G. Gómez (2017-05). The anticipated odds ratios to decide the choice of a primary binary endpoint. Conference of the Eastern Mediterranean Region of the International Biometric Society.
  12. M. Bofill and G. Gómez (2017-01-20). Sample size determination using composite binary endpoints. Reunión general Biostatnet.
  13. G. Gómez, M. Gómez and M. Bofill (2016-12-11). Planning clinical trials with CompARE. International Conference of the ERCIM Working Group on Computing & Statistics.
  14. G. Gómez, M. Gómez and M. Bofill(2016-09-05). Planning clinical trials involving composite endpoints. Congreso Nacional de Estadística e Investigación Operativa.
  15. M. Bofill and G. Gómez(2016-08-23). The efficient choice of a primary binary endpoint for sample size assessment. International Society for Clinical Biostatistics.

Outreach


  1. Introduction to CompARE for Binary Endpoints

Contact Us


Contact info


C/ Jordi Girona 1-3, Edifici C5 planta 2
Barcelona, Barcelona 08034 · Spain